ANGULAR LIGHT-SCATTERING STUDIES ON ISOLATED MITOCHONDRIA

Angular Light-scattering Studies on Isolated Mitochondria

Angular light-scattering studies have been carried out on suspensions of isolated rat liver mitochondria. The angular scatter pattern has a large forward component, typical of large particles. Changes in dissymmetry and in the intensity of light scattered at 90 degrees have been correlated with changes in optical density during the course of mitochondrial swelling and contraction. Such changes ...

Angular light scattering studies using low-coherence interferometry

A modified Michelson interferometer is used to measure path-length resolved angular distributions of light backscattered by turbid media. The path length resolution is obtained by exploiting the coherence properties of a broadband source. The angular distribution is mapped out using a simple optical system to scan the angle at which the reference field intersects the detector plane. Angular sca...

Toxicity of atorvastatin on isolated brain mitochondria

Background: Although the bio kinetics, metabolism and chemical toxicity of Atorvastatin are well known, until recently little attention was paid to the potential neurotoxic effect of Atorvastatin (Atv). Regarding the concrete evidences indicating Atv may reduce Coenzyme Q10 (CoQ10) levels through blockage of  metalonate cycle, the present work aims to determine if Atorvastatin may provide toxic...

Light Scattering Studies on Lecithin Micellar Solutions

Light scattering studies on DNA condensation.

DNA condenses into compact particles when mixed with dilute solutions of trivalent cations such as spermidine or hexammine cobalt (111) (CoHex) [ 1-41. These particles are approximately the size of bacteriophage capsids and generally have a toroidal or rodlike morphology. Remarkably, the size of the condensed particles is quite insensitive to the size of the DNA [3, 51. Particles formed with T7...